Allogeneic Stem Cell Transplantation for Aplastic Anemia

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Allogeneic peripheral blood stem cell transplantation in aplastic anemia.

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Allogeneic hematopoietic stem cell transplantation in children with aplastic anemia.

The aim of this study was to prospectively investigate the efficacy and safety of fully matched allogeneic hematopoietic stem cell transplants in children with severe aplastic anemia in China. A total of twenty patients with severe aplastic anemia were enrolled in our study. Thirteen cases underwent transplantation with fully human leukocyte antigen (HLA)-matched, granulocyte-colony stimulating...

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Allogeneic transplantation for aplastic anemia.

OBJECTIVE To discuss the role of allogeneic transplantation for the treatment of severe aplastic anemia. METHODS Published reports for treatment of severe aplastic anemia were searched with Medline. Search terms included severe aplastic anemia, HLA-matched sibling, unrelated donor, hematopoietic stem cell transplantation. RESULTS Survival after HLA-matched sibling donor transplantation is a...

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Successful allogeneic stem cell transplantation with fludarabine-based conditioning regimen in severe aplastic anemia.

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In vitro coculture studies were performed in five patients with severe aplastic anemia (SAA) and their normal HLA-matched donors before and after allogeneic bone marrow transplantation (BMT) to determine whether the erythropoietic function of T cells is abnormal in this disorder. These coculture studies used fresh or cryopreserved marrow T lymphocytes with fresh or cryopreserved marrow T cell-d...

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ژورنال

عنوان ژورنال: Biology of Blood and Marrow Transplantation

سال: 2007

ISSN: 1083-8791

DOI: 10.1016/j.bbmt.2007.02.005